Dr. Jeongbin Park

(last updated: Jul 10, 2024)

(The latest version of this CV is available at: https://jeongbinpark.com/cv)

Address:

Room #413, Kyung-Ahm Engineering Building, Busandaehak-ro 49,
Mulgeum-eup, Yangsan-si, 50612 Republic of Korea

email:

jeongbin.park at pusan.ac.kr

Tel.:

+82-51-510-8597

EDUCATION

2016 - 2020

Dr. rer. nat. (Ph. D. equivalent) in Biology, Heidelberg University, Germany

2012 - 2014

M. Sc. in Physics, Seoul National University, Korea

2008 - 2012

B. Sc. in Physics, Pusan National University, Korea

WORK EXPERIENCE

2022 - Present

Assistant Professor,
School of Biomedical Convergence Engineering, Pusan National University

2020 - 2022

Postdoctoral Researcher,
Division of Computational Genomics and System Genetics, German Cancer Research Center (DKFZ)
(Advisor: Prof. Oliver Stegle)

2018 - 2020

Researcher (PhD student),
Digital Health Center, Berlin Institute of Health (BIH) / Charité
(Advisor: Prof. Roland Eils)

2016 - 2018

Researcher (PhD student),
Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ)
(Advisor: Prof. Roland Eils)

2015 - 2016

Research Collaboration,
Molecular Genome Engineering Laboratory, Hanyang University
(Research collaborator: Prof. Sangsu Bae)

2014 - 2015

Research Collaboration,
Genome Engineering Laboratory, Seoul National University
(Research collaborator: Dr. Sangsu Bae)

2012 - 2014

Researcher (MSc student),
Single Molecule Biophysics Laboratory, Seoul National University
(Advisor: Prof. Sungchul Hohng)

SERVICE

Scientific Community:

  • Korean Society for Bioinformatics (KSBI), Public Affairs Committee Member, 2023 / Academic Affairs Committee Member, 2024

  • Korea Genome Organization (KOGO), Information and Computing Committee Member, 2023-2024

Ad-hoc Journal Reviewer:

  • Bioinformatics, eLife, Communications Biology, NAR: Genomics and Bioinformatics, Scientific Reports, BMC Genomics, Journal of Open Source Software (JOSS)

Book Translation:

Open Source Contribution:

TEACHING

At PNU:

  • “Bioinformatics”, “UNIX Fundamentals”, “Introduction to Biomedical Informatics”, “Object-oriented Programming”, “Web Programming”, School of Biomedical Convergence Engineering, Pusan National University

  • “Statistical Genomics”, “Clinical and Genomic Informatics”, Graduate School of Genomic Data Science, Pusan National University

Before PNU:

  • Invited lecture “Spatial transcriptomics” at “Single cell RNA-seq data analysis with R” (sponsored by the ELIXIR EXCELERATE project). CSC, Espoo, Finland. 29 May 2019.

  • Student supervision, 3 student research interns (including 1 co-supervision), Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Germany. Jul 2016 - Feb 2018.

  • “Methoden der Bioinformatik - Python” (lecture assistant), Faculty of Biosciences, Heidelberg University, WS 2016 and WS 2017.

  • “Physics Laboratory” (teaching assistant), Department of Physics, Seoul National University, SS 2012.

CONFERENCE PROCEEDINGS

Martina K Zowada, Stephan M Tirier, Sebastian M Dieter, Teresa Krieger, Ava Oberlack, Robert L Chua, Mario Huerta, Foo Wei Ten, Karin Laaber, Jeongbin Park, Katharina Jechow, Torsten Müller, Mathias Kalxdorf, Mark Kriegsmann, Katharina Kriegsmann, Friederike Herbst, Jeroen Krijgsveld, Martin Schneider, Roland Eils, Hanno Glimm, Christian Conrad, Claudia R Ball, “Transcriptional heterogeneity identifies functional states of tumor-initiating cell differentiation in human colorectal cancer”, Cancer Research 80 (16 Supplement), Abstract nr. 1491 (2020).

Cristina Lopez, Rabea Wagener, Kortine Kleinheinz, Julia Bausinger, Sietse M Aukema, Inga Nagel, Umut H Toprak, Julian Seufert, Janine Altmueller, Holger Thiele, Christof Schneider, Julia Kolarova, Jeongbin Park, Daniel Huebschmann, Eva M Murga Penas, Hans G Drexler, Andishe Attarbaschi, Randi Hovland, Eigil Kjeldsen, Michael Kneba, Udo Kontny, Laurence de Leval, Peter Nuernberg, Ilske Oschlies, David Oscier, Brigitte Schlegelberger, Stephan Stilgenbauer, Wilhelm Woessmann, Matthias Schlesner, Birgit Burkhardt, Wolfram Klapper, Elaine S Jaffe, Ralf Kueppers, Reiner Siebert, “IG-MYC-positive leukemia and lymphoma with precursor B-cell phenotype are genetically and epigenetically distinct from Burkitt lymphomas”, British Journal of Haematology 182 (S1), 19-21, Abstract nr. 23 (2018).

Alain Coulais, Marc Schellens, Gilles Duvert, Jeongbin Park, Orion Poplawski, Sylwester Arabas, Stephane Erard, Benjamin Laurent, Mathieu Pinter, Nodar Kasradze, Mouadh Ayad, “Scaling GDL for multi-cores to process Planck HFI beams Monte Carlo on HPC”, Astronomical Data Analysis Software and Systems XXIII 485, 331 (2014). [cited: 1]

PUBLICATIONS

Yujin Kim, Minwoo Jeong, In Gyeong Koh, Chanhee Kim, Hyeji Lee, Jae Hyun Kim, Ronald Yurko, Il Bin Kim, Jeongbin Park, Donna M Werling, Stephan J Sanders, Joon-Yong An, “CWAS-Plus: Estimating category-wide association of rare noncoding variation from whole-genome sequencing data with cell-type-specific functional data”, medRxiv (2024).

Teng-Feng Li, Arthur Lang, Paul Rothhaar, Oliver Gruenvogel, Ombretta Colasanti, Santa Mariela Olivera Ugarte, Jannik Traut, Antonio Piras, Nelson Acosta-Rivero, Vladimir Goncalves Magalhaes, Emely Springer, Andreas Betz, Hao-En Huang, Jeongbin Park, Ruiyue Qiu, Gnimah Eva Gnouamozi, Ann-Kathrin Mehnert, Viet Loan Dao Thi, Stephan Urban, Martina Muckenthaler, Matthias Schlesner, Dirk Wohlleber, Marco Binder, Ralf Bartenschlager, Andreas Pichlmair, Volker Lohmann, “RBM39 shapes innate immunity through transcriptional and splicing control of IRF3 and other key factors”, bioRxiv, 2023.10. 13.562221 (2023). [cited: 2]

Yun Zhang#, Jeremy A Miller#, Jeongbin Park#, Boudewijn P Lelieveldt, Brian Long, Tamim Abdelaal, Brian D Aevermann, Tommaso Biancalani, Charles Comiter, Oleh Dzyubachyk, Jeroen Eggermont, Christoffer Mattsson Langseth, Viktor Petukhov, Gabriele Scalia, Eeshit Dhaval Vaishnav, Yilin Zhao, Ed S Lein, Richard H Scheuermann, “Reference-based cell type matching of in situ image-based spatial transcriptomics data on primary visual cortex of mouse brain”, Scientific Reports 13 (1), 9567 (2023). [cited: 14]

Jeongbin Park, Nagarajan Paramasivam, “PyOncoPrint: a python package for plotting OncoPrints”, Genomics & Informatics 21 (1), e14 (2023).

Seul Lee, Taein Kim, Min-Soo Choi, Yejin Kwak, Jeongbin Park, Sung Ju Hwang, Sang-Gyu Kim, “READRetro: Natural Product Biosynthesis Planning with Retrieval-Augmented Dual-View Retrosynthesis”, bioRxiv, 2023.03. 21.533616 (2023).

Brian Long, Jeremy Miller, The SpaceTx Consortium, “SpaceTx: A Roadmap for Benchmarking Spatial Transcriptomics Exploration of the Brain”, arXiv, 2301.08436 (2023). [cited: 16]

Jeongbin Park, Gilles Duvert, Alain Coulais, Gregory V Jung, Sylwester Arabas, Brian Barker, Takeshi Enomoto, Sylvain Flinois, Oliver Gressel, Tomas Hillberg, Thibault Huillet, Jan Kohnert, Orion Poplawski, Eloi Rozier de Linage, Remi A Solås, Luke Stagner, Ole Streicher, James Tappin, Thierry Thomas, Jingwei Wang, Christian Wimmer, “GNU Data Language 1.0: a free/libre and open-source drop-in replacement for IDL/PV-WAVE”, Journal of Open Source Software 7 (80), 4633 (2022). [cited: 2]

Jeongbin Park#, Wonyl Choi#, Sebastian Tiesmeyer, Brian Long, Lars E Borm, Emma Garren, Thuc Nghi Nguyen, Bosiljka Tasic, Simone Codeluppi, Tobias Graf, Matthias Schlesner, Oliver Stegle, Roland Eils, Naveed Ishaque, “Cell segmentation-free inference of cell types from in situ transcriptomics data”, Nature Communications 12, 3545 (2021). [cited: 94]

Martina K Zowada, Stephan M Tirier, Sebastian M Dieter, Teresa G Krieger, Ava Oberlack, Robert Lorenz Chua, Mario Huerta, Foo Wei Ten, Karin Laaber, Jeongbin Park, Katharina Jechow, Torsten Müller, Mathias Kalxdorf, Mark Kriegsmann, Katharina Kriegsmann, Friederike Herbst, Jeroen Krijgsveld, Martin Schneider, Roland Eils, Hanno Glimm, Christian Conrad, Claudia R Ball, “Functional states in tumor-initiating cell differentiation in human colorectal cancer”, Cancers 13 (5), 1097 (2021). [cited: 10]

Teresa G Krieger, Stephan M Tirier, Jeongbin Park, Katharina Jechow, Tanja Eisemann, Heike Peterziel, Peter Angel, Roland Eils, Christian Conrad, “Modeling glioblastoma invasion using human brain organoids and single-cell transcriptomics”, Neuro-oncology, noaa091 (2020). [cited: 97]

Andres Quintero, Daniel Hübschmann, Nils Kurzawa, Sebastian Steinhauser, Philipp Rentzsch, Stephen Krämer, Carolin Andresen, Jeongbin Park, Roland Eils, Matthias Schlesner, Carl Herrmann, “ShinyButchR: Interactive NMF-based decomposition workflow of genome-scale datasets”, Biology Methods and Protocols 5 (1), bpaa022 (2020). [cited: 15]

Stephan M Tirier, Jeongbin Park, Friedrich Preußer, Lisa Amrhein, Zuguang Gu, Simon Steiger, Jan-Philipp Mallm, Teresa Krieger, Marcel Waschow, Björn Eismann, Marta Gut, Ivo G Gut, Karsten Rippe, Matthias Schlesner, Fabian Theis, Christiane Fuchs, Claudia R Ball, Hanno Glimm, Roland Eils, Christian Conrad, “pheno-seq–linking visual features and gene expression in 3D cell culture systems”, Scientific Reports 9, 12367 (2019). [cited: 22]

Gue-Ho Hwang#, Jeongbin Park#, Kayeong Lim, Sunghyun Kim, Jihyeon Yu, Eunchong Yu, Sang-Tae Kim, Roland Eils, Jin-Soo Kim, Sangsu Bae, “Web-based design and analysis tools for CRISPR base editing”, BMC Bioinformatics 19, 542 (2018). [cited: 159]

Rabea Wagener, Cristina López, Kortine Kleinheinz, Julia Bausinger, Sietse M Aukema, Inga Nagel, Umut H Toprak, Julian Seufert, Janine Altmüller, Holger Thiele, Christof Schneider, Julia Kolarova, Jeongbin Park, Daniel Hübschmann, Eva M Murga Penas, Hans G Drexler, Andishe Attarbaschi, Randi Hovland, Eigil Kjeldsen, Michael Kneba, Udo Kontny, Laurence De Leval, Peter Nürnberg, Ilske Oschlies, David Oscier, Brigitte Schlegelberger, Stephan Stilgenbauer, Wilhelm Wössmann, Matthias Schlesner, Birgit Burkhardt, Wolfram Klapper, Elaine S Jaffe, Ralf Küppers, Reiner Siebert, “IG-MYC+ neoplasms with precursor B-cell phenotype are molecularly distinct from Burkitt lymphomas”, Blood 132 (21), 2280-2285 (2018). [cited: 63]

Jeongbin Park#, Liam H Childs#, Matthias Schlesner, Roland Eils, “HTSlib-js: developer toolkit for a client-side JavaScript interface for HTSlib”, bioRxiv, 397935 (2018). [cited: 1]

Sang-Tae Kim#, Jeongbin Park#, Daesik Kim, Kyoungmi Kim, Sangsu Bae, Matthias Schlesner, Jin-Soo Kim, “Response to “Unexpected mutations after CRISPR–Cas9 editing in vivo””, Nature Methods 15 (4), 239-240 (2018). [cited: 47]

Jeongbin Park, Sangsu Bae, “Cpf1-Database: web-based genome-wide guide RNA library design for gene knockout screens using CRISPR-Cpf1”, Bioinformatics 34 (6), 1077-1079 (2018). [cited: 30]

Manuel Rodríguez-Paredes, Felix Bormann, Günter Raddatz, Julian Gutekunst, Carlota Lucena-Porcel, Florian Köhler, Elisabeth Wurzer, Katrin Schmidt, Stefan Gallinat, Horst Wenck, Joachim Röwert-Huber, Evgeniya Denisova, Lars Feuerbach, Jeongbin Park, Benedikt Brors, Esther Herpel, Ingo Nindl, Thomas G Hofmann, Marc Winnefeld, Frank Lyko, “Methylation profiling identifies two subclasses of squamous cell carcinoma related to distinct cells of origin”, Nature Communications 9, 577 (2018). [cited: 72]

Daniel B Lipka, Tania Witte, Reka Toth, Jing Yang, Manuel Wiesenfarth, Peter Nöllke, Alexandra Fischer, David Brocks, Zuguang Gu, Jeongbin Park, Brigitte Strahm, Marcin Wlodarski, Ayami Yoshimi, Rainer Claus, Michael Lübbert, Hauke Busch, Melanie Boerries, Mark Hartmann, Maximilian Schönung, Umut Kilik, Jens Langstein, Justyna A Wierzbinska, Caroline Pabst, Swati Garg, Albert Catalá, Barbara De Moerloose, Michael Dworzak, Henrik Hasle, Franco Locatelli, Riccardo Masetti, Markus Schmugge, Owen Smith, Jan Stary, Marek Ussowicz, Marry M Van Den Heuvel-Eibrink, Yassen Assenov, Matthias Schlesner, Charlotte Niemeyer, Christian Flotho, Christoph Plass, “RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia”, Nature Communications 8, 2126 (2017). [cited: 114]

Julia Jabs, Franziska M Zickgraf, Jeongbin Park, Steve Wagner, Xiaoqi Jiang, Katharina Jechow, Kortine Kleinheinz, Umut H Toprak, Marc A Schneider, Michael Meister, Saskia Spaich, Marc Sütterlin, Matthias Schlesner, Andreas Trumpp, Martin Sprick, Roland Eils, Christian Conrad, “Screening drug effects in patient‐derived cancer cells links organoid responses to genome alterations”, Molecular Systems Biology 13, 955 (2017). [cited: 205]

Daniel Hüebschmann, Nils Kurzawa, Sebastian Steinhauser, Philipp Rentzsch, Stephen Krämer, Carolin Andresen, Jeongbin Park, Roland Eils, Matthias Schlesner, Carl Herrmann, “Deciphering programs of transcriptional regulation by combined deconvolution of multiple omics layers”, bioRxiv, 199547 (2017). [cited: 8]

Heon Seok Kim, Kyungjin Lee, Sangsu Bae, Jeongbin Park, Chong-Kyo Lee, Meehyein Kim, Eunji Kim, Minju Kim, Seokjoong Kim, Chonsaeng Kim, Jin-Soo Kim, “CRISPR/Cas9-mediated gene knockout screens and target identification via whole-genome sequencing uncover host genes required for picornavirus infection”, Journal of Biological Chemistry 292 (25), 10664-10671 (2017). [cited: 45]

Jeongbin Park, Liam Childs, Daesik Kim, Gue-Ho Hwang, Sunghyun Kim, Sang-Tae Kim, Jin-Soo Kim, Sangsu Bae, “Digenome-seq web tool for profiling CRISPR specificity”, Nature Methods 14 (6), 548-549 (2017). [cited: 45]

Jeongbin Park, Kayeong Lim, Jin-Soo Kim, Sangsu Bae, “Cas-analyzer: an online tool for assessing genome editing results using NGS data”, Bioinformatics 33 (2), 286-288 (2017). [cited: 361]

Jeongbin Park, Jin-Soo Kim, Sangsu Bae, “Cas-Database: web-based genome-wide guide RNA library design for gene knockout screens using CRISPR-Cas9”, Bioinformatics 32 (13), 2017-2023 (2016). [cited: 47]

Daesik Kim, Sojung Kim, Sunghyun Kim, Jeongbin Park, Jin-Soo Kim, “Genome-wide target specificities of CRISPR-Cas9 nucleases revealed by multiplex Digenome-seq”, Genome Research 26 (3), 406-415 (2016). [cited: 233]

Jeongbin Park, Sangsu Bae, Jin-Soo Kim, “Cas-Designer: a web-based tool for choice of CRISPR-Cas9 target sites”, Bioinformatics 31 (24), 4014-4016 (2015). [cited: 412]

Daesik Kim, Sangsu Bae, Jeongbin Park, Eunji Kim, Seokjoong Kim, Hye Ryeong Yu, Jinha Hwang, Jong-Il Kim, Jin-Soo Kim, “Digenome-seq: genome-wide profiling of CRISPR-Cas9 off-target effects in human cells”, Nature Methods 12 (3), 237-243 (2015). [cited: 1095]

Sangsu Bae#, Jeongbin Park#, Jin-Soo Kim, “Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases”, Bioinformatics 30 (10), 1473-1475 (2014). [cited: 1958]

Moon-Hyeong Seo, Jeongbin Park, Eunkyung Kim, Sungchul Hohng, Hak-Sung Kim, “Protein conformational dynamics dictate the binding affinity for a ligand”, Nature Communications 5, 3724 (2014). [cited: 168]

Total Citations: 5336, H-index: 19

  • #: Joint first authors.

  • The citation numbers were retrieved from Google Scholar.